New articles in the GANM Library - Non-communicable diseases and well-being

Dear GANM community,


In this week’s edition of the GANM Research Library Brief we would like to share three articles centering around the topic of critical care nursing, strokes, and well-being.



Yoo, M. S., Zhu, S., Lu, Y., … & Liu, V. X. (2021). Association of positive fluid balance at discharge after sepsis management with 30-day readmission. JAMA Network Open, 4(6):e216105. doi:10.1001/jamanetworkopen.2021.6105


Recently in JAMA, an article looked at the association between positive fluid balance at the time of discharge and 30-day readmission fir non-critically ill patients with sepsis. This was done via a cohort study of approximately 57,000 patients all of who were adults hospitalized with sepsis. Overall, there was no association between the two variables, however, this could be due to an incomplete capture of the data points such as intake and output and other founding variables. Further investigation is needed.



de Havenon, A., Johnston, S. C., Easton, J. D., … & Yaghi, S. (2021). Evaluation of systolic blood pressure, use of aspirin and clopidogrel, and stroke recurrence in the platelet-oriented inhibition in new TIA and minor ischemic stroke trial. JAMA Network Open, 4(6):e2112551. doi:10.1001/jamanetworkopen.2021.12551


For those who have had a transient ischemic attack (TIA) and stroke, is there an association between blood pressure and dual antiplatelet therapy and rates of secondary stroke within a 90-day period? In this analysis of 4,781 patients, all having a baseline systolic blood pressure of less than 140mmHg there was a significant reduction in rates. On there other hand, those with a systolic blood pressure greater than or equal t 140 mmHg was not benefited by dual therapy.  Overall, more research is needed to clearly evaluate these findings. 



Sundaresh, R., Yi, Y., Harvey, T. D., … & Wang, E. A. (2021). Exposure to family member incarceration and adult well-being in the United States. JAMA Network Open, 4(5):e2111821. doi:10.1001/jamanetworkopen.2021.11821


Incarceration of family members may impact well-being and projected life expectancy, or at least this is the topic researchers have recently looked in to. In a cross-sectional study of 2,815 people there was an association of lower well-being and about a 2.6-year reduction in life expectancy compared to those who did not have a family member that was incarcerated. Furthermore, when broken up by race, those who are Black have a 0.5 fewer years of life expectancy. Overall, these data suggest that demarcating may improve population health and combat racial disparities. 




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