Dear GANM community,
Cardiovascular disease, high blood pressure, and cancer all have one thing in common – each impact vast numbers of individuals across the globe. In this week’s edition of the GANM library research brief we bring to you three articles published in JAMA that further discuss those topics.
Abdalla, S. M., Yu, S., & Galea, S. (2020). Trends in cardiovascular disease prevalence by income level in the United States. JAMA Network Open; 3(9):e2018150. doi:10.1001/jamanetworkopen.2020.18150
Income level or socioeconomic status (SES) are directly linked to worse health outcomes in the United States. In a cross-sectional study with 44,986 participants the question of how the burden of CVD in the U.S. differed between those with the most medical resources versus those with less resources. Overall, massive disparities were found including CVD being reportedly less frequently in those with high income. This is a call for better policy and public health efforts.
Tapia-Conyer, R., Alegre-Díaz, J., Gnatiuc, L., et al. (2020). Association of blood pressure with cause-specific mortality in Mexican adults. JAMA Network Open; 3(9):e2018141. doi:10.1001/jamanetworkopen.2020.18141
In a recent study, researchers sought to understand the association between blood pressure and mortality in Mexican adults and how it varies with conditions such as diabetes. Of the 133,613 study participants approximately 12.7% had diabetes with about half being uncontrolled. In all, blood pressure was strongly associated with vascular and kidney-related mortality. Thus, there may be a need for more blood-pressure medication in Mexico, especially in those with diabetes.
Niraula, S., Biswanger, N., Hu, P., Lambert, P., & Decker, K. (2020). Incidence, characteristics, and outcomes of interval breast cancers compared with screening-detected breast cancers. JAMA Network Open; 3(9):e2018179. doi:10.1001/jamanetworkopen.2020.18179
What are the differences and similarities in the characteristics and outcomes between those diagnosed via mammographic screening vs. those diagnosed between screening mammograms? This is the question researchers explored in a recent JAMA article. Of 69,025 women there were 1,687 diagnoses and 225 deaths. Interval cancers were more likely to be of high grade and estrogen receptor negative. Mortality was statistically significantly higher in interval cancers as well – approximately 3-fold. This article expresses the need for reduced incidence, improved detection, and more health promotion.