Dear GANM community,
In this week’s edition of the GANM library we bring to you two research articles published in The Lancet and through The JAMA network. These two articles center around the current pandemic in realtion to the pediatric population and the prevalence of delirium in those diagnosed with COVID-19.
Heald-Sargent, T., Muller, W. J., Zheng, X., Rippe, J., Patel, A. B., & Kociolek, L. K. (2020). Age-related differences in nasopharyngeal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) levels in patients with mild to moderate coronavirus disease 2019 (COVID-19). JAMA Pediatrics.doi:10.1001/jamapediatrics.2020.3651
Children diagnosed with COVID-19 typically present with mild symptoms when compared to adults. This study sought to understand transmission among the pediatric population and includes findings which include children younger than 5 years old carry increased viral particles in the nasopharynx when compared to those over the age of 5.
Poloni, T. E., Carlos, A. F., Cairati, M., Cutaia, C., Medici, V., Marelli, E., Ferrari, D., Galli, A., Bognetti, P., Davin, A., Cirrincione, A., Ceretti, A., Cereda, C., Ceroni, M., Tronconi, L., Vitali, S., & Guaita, A. (2020). Prevalence and prognostic value of delirium as the initial presentation of COVID-19 in the elderly with dementia: An Italian retrospective study. https://doi.org/10.1016/j.eclinm.2020.100490
Delirium is of the most common symptoms in patients diagnosed with COIVD-19. This condition complicates treatment and care of the older adult patient. Thus, researchers aimed to identify the prevalence and prognostic significance of delirium in the onset of CVOID-19. Findings include delirium being present in 36.8% of subjects older than 85 years old included int eh study. Additionally, it is believed delirium occurrence in older adults may present in the prodromal phase of the infection.