Dear GANM community,
As parts of the United States and the world begin to open back up, we continue to monitor unfolding research about COVID-19. This week’s addition to the GANM Library includes recently published articles on coronavirus and pregnancy, hypertension during pregnancy as it relates to COVID-19, and the risk for early neurodevelopment outcomes in the context of antiepileptic drugs.
COVID-19 related articles:
Breslin, N., Baptiste, C., Miller, R., Fuchs, K., Goffman, D., Gyamfi-Bannerman, C., & D’Alton, M. (2020). Coronavirus disease 2019 in pregnancy: Early lessons. American Journal of Obstetrics & Gynecology MFM, 2(2). https://doi.org/10.1016/j.ajogmf.2020.100111
In an article published recently this month researches sought to understand the impact of COVID-19 on pregnancy. In summary, 7 case reports of which 4 were admitted to the hospital for supportive therapy and 2 others that required intensive care. As for the 2 ICU patients both were asymptomatic upon presentation.
Magee, L. A., Khaili, A., Von Dadelszen, P. (2020). Pregnancy hypertension diagnosis and care in COVID-19 era and beyond. Ultrasound in Obstetrics & Gynecology. https://doi.org/10.1002/uog.22115
As of today COVID-19 has impacted every individual on the planet in some capacity and the same is true for those that are hypertensive and pregnant. Due to the spread of the SARS-CoV-2 virus many women that are pregnant or trying to become pregnant have been advised to stay home. This article seeks to discuss the importance of Home blood pressure monitoring (HBPM) as well as array of therapeutic treatments for pregnant women during this uncertain time.
Non COVID-19 related articles:
Blotiere, P., Miranda, S., Weill, A., Mikaeloff, Y., Peyre, H., Ramus, F., Mahmoud, Z., Coste, J., &Dray-Spira, R. (2020). Risk of early developmental outcomes associated with prenatal exposure to the antiepileptic drugs most commonly used during pregnancy: A French nationwide population-based cohort study. British Medical Journal, 10(6). doi:10.1136/ bmjopen-2019-034829
Researchers across France recently collaborated on a project to understand the risks of children developing neurodevelopmental issues upon pre-natal exposure to antiepileptic drugs. In a cohort of 9034 children, of which various numbers were exposed to an array of antiepileptic drugs (lamotrigine, pregabalin, clonazepam, etc.), only those exposed to valproic acid were found to be at a higher risk (991 children). Researchers conclude that more research must be done with longer follow-up of each child.